ABSTRACT
To study clinical characteristics and mycology of cutaneous candidiasis in Ahwaz [Iran]. Four hundered sixty one patients were examined for cutaneous candidiasis over a period of 4 years from different medical mycology laboratories in Ahwaz. Skin scrapings, nail clippings and swabs were obtained from the lesions of 461 subjects. Samples were prepared by KOH, Gram and methylene blue techniques. The samples were also cultured on Sabouraud's dextrose agar with chloramphenicol [SC] and kept at 37°C for one week. Isolates were identified based on germ tube test, production chlamydoconidia in cornmeal agar, growing at 45°C and API 20 C AUX kits. 257 patients 179 female and 78 male [55.7%] were observed to have candidiasis. Onychomycosis [64.2%] was the most common form of candidiasis, followed by groin candidiasis 21% and toenail candidiasis [14.8%]. Candida albicans [49.4%] was most common isolate from patients. Cutaneous candidiasis is an important candida infection in women at the ages of 21-40 years in Ahwaz and C. albicans is the commonest etiologic agent
Subject(s)
Humans , Male , Female , Candidiasis, Cutaneous/etiology , Candida albicans , OnychomycosisABSTRACT
A clinical and prospective study was conducted to determine the prevalence and pattern of cutaneous manifestations of thyroid disease. Out of 100 patients examined, 61 were of hyperthyroidism and 31 were hypothyroid. The common cutaneous manifestations of hyperthyroidism were; loss of weight [90%] and anaemia [85.3%] followed by increased temperature, hair loss, onycholysis, soft velvety skin, pruritus, urticaria, diffuse pigmentation, telangiectasia and purpura. Exophthalmos was present in 98.68% of cases. The other associated diseases were vitiligo, alopecia areata and mucocutaneous candidiasis. In hypothyroidism the most common finding was coarse, rough and dry skin [90%], anaemia [79.45%], followed by hair loss, rough brittle nails, periorbital puffiness, cool skin and eczema craquele. Xanthelasma palpebrum was found in 5.12% of cases. Pallor in hypothyroidism, anaemia, nail changes and diffuse hair loss in hyperthyroidism had much higher incidence in our study. The age of thyroid disorders were also seen at a younger age in comparison with the other studies
Subject(s)
Humans , Male , Female , Thyroid Diseases/complications , Candidiasis, Cutaneous/etiology , Thyroid Function TestsABSTRACT
La Diabetes Mellitus es una patología frecuente en la población, caracterizada por el aumento del nivel plasmático de la glucosa y por disturbios en el metabolismo de carbohidratos y lípidos. según diversos estudios, entre un 30 por ciento y un 100 por ciento de los pacientes diabéticos presentan alteraciones en la piel, las cuales pueden clasificarse en 4 grandes grupos: manifestaciones cutáneas relacionadas con descompensación metabólica, tales como infecciones de diversos tipos, aquellas relacionadas con complicaciones degenerativas crónicas como el pié diabético, desórdenes cutáneos que son más comunes en Diabetes Mellitus y que no se correlacionan con descompensación metabólica ni con cambios degenerativos como la acantosis nigricans y, por último, reacciones como consecuencia del tratamiento de la Diabetes Mellitus, entre las cuales se mencionan las erupciones morbiliformes
Subject(s)
Humans , Diabetes Mellitus/complications , Skin Diseases/etiology , Diabetic Angiopathies/complications , Candidiasis, Cutaneous/etiology , Skin Diseases, Vesiculobullous/etiology , Granuloma Annulare/etiology , Necrobiosis Lipoidica/etiology , Diabetic Foot/etiology , Vitiligo/etiology , Xanthomatosis/etiologyABSTRACT
Introducción. La dermatitis de la zona del pañal (DZP), común en lactantes, se agrava frecuentemente con infecciones, principalmente por Candida albicans. Objetivo. Comparar la eficacia y tolerancia a la terbinafina en crema contra la de ketoconazol en crema en candidiosis de la zona del pañal. Material y métodos. Se realizó un ensayo clínico abierto, comparativo, aletorizado, separando 2 grupos, indicandoseles aplicar terbinafina en crema una vez al día durante 14 días al primer grupo y ketoconazol 2 veces al día, por mismo periodo, al segundo grupo. El seguimiento se realizó por 4 semanas. Resultados. Ingresaron 52 pacientes; 28 en el grupo de terbinafina, 24 en el ketoconazol; 28 del sexo masculino y 24 del femenino. Hubo un sólo caso de reacción adversa en el grupo de terbinafina y consistió en incremento del eritema y prurito. El resto de parámetros evolucionó en forma similar. Conclusiones. Los análisis estadísticos no reportan diferencia significativa. Se considera a la terbinafina como alterativa en una circunstancia clínica no estudiada antes